Antimicrobial Activity of Butyrate Glycerides Toward Salmonella Typhimurium and Clostridium perfring

Objective of the study To evaluate the antimicrobial activity of butyrate glycerides (derivatives of butyric acid) against two common pathogenic bacteria in poultry:

• Salmonella Typhimurium

• Clostridium perfringens

Methodology In vitro tests were conducted to observe the inhibitory effect of butyrate glycerides on bacterial growth. Different concentrations were compared to determine dose-dependent efficacy.

Key Results

• Butyrate glycerides significantly inhibited the growth of Salmonella and Clostridium.

• Antimicrobial activity was proportional to the administered dose.

• Butyrate glycerides were found to be less corrosive and more palatable than free butyric acid, making them more suitable for feed inclusion.

Conclusion Butyrate glycerides are an effective and safe alternative to antibiotics for controlling intestinal pathogens in poultry. Their use can improve digestive health and reduce the incidence of enteric diseases such as necrotic enteritis.

Full article: https://www.sciencedirect.com/science/article/pii/S0032579119422748